O20 ‐ Human rhinovirus replication‐dependent induction of micro‐RNAs in human bronchial epithelial cells
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چکیده
منابع مشابه
O20 - Human rhinovirus replication-dependent induction of micro-RNAs in human bronchial epithelial cells
Background Micro-RNAs (miRNAs) are a class of small non-coding RNA molecules that function though post transcriptional regulation of gene expression by a process termed RNA interference (RNAi). RNAi–mediated targeting of viral RNAs is recognized as an antiviral defense mechanism. The epigenetic effect of miRNAs can either be direct, by interfering with virus genome, or indirect, through downreg...
متن کاملHuman rhinovirus infection of human bronchial epithelial cells results in migration of human bronchial fibroblast cells
Background Recent studies have demonstrated that structural changes in the airways characteristic of asthma, collectively referred to as airway remodeling, occur in young children even prior to the diagnosis of asthma. Young children who experience human rhinovirus (HRV)-associated wheezing illness within the first three years of life are at increased risk for the subsequent development of asth...
متن کاملHuman rhinovirus infection of human bronchial epithelial cells results in migration of human airway smooth muscle cells
Background Young children who experience human rhinovirus (HRV)-associated wheezing illnesses are more likely to develop subsequent asthma [1]. This has led to the hypothesis that HRV infection may be involved in the pathogenesis of airway remodeling in asthma [2]. Increased airway smooth muscle (ASM) mass, in which ASM cells are in close proximity to the subepithelial region, is a characterist...
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Objective(s): Endometriosis is a complex gynecologic disease with unknown etiology. Noscapine has been introduced as a cancer cell suppressor. Endometriosis was considered as a cancer like disorder, The aim of present study was to investigate noscapine apoptotic effect on human endometriotic epithelial and stromal cells in vitro. Materials and Methods:In this in vitro study, endometrial biopsie...
متن کاملRhinovirus replication causes RANTES production in primary bronchial epithelial cells.
The mechanisms by which rhinovirus (RV) infections produce lower airway symptoms in asthmatic individuals are not fully established. To determine effects of RV infection on lung epithelial cells, primary human bronchial epithelial (BE) cells were infected with either RV16 or RV49, and viral replication, cell viability, and cell activation were measured. Both viral serotypes replicated in BE cel...
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ژورنال
عنوان ژورنال: Clinical and Translational Allergy
سال: 2014
ISSN: 2045-7022,2045-7022
DOI: 10.1186/2045-7022-4-s1-o20